Some patients experience that the L-Mesitran Ointment and Soft sometimes can cause a stinging sensation. This is due to the osmotic action of the sugars in the honey.

The L-Mesitran Ointment holds more honey than the Soft version, therefore the stinging sensation can be more. This usually subsides after a short while. When it does not subside, one can either use a small painkiller or wetten the gauze, wich was placed on top of the ointment, with some purified water. This will diminish the osmotic action, and in that case the stinging sensation. Practice learns that as soon as the wounds are well on their way towards healing, the stinging is absent.